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  • Tomowave – Maestro

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  • Tomowave – Maestro

  • Tomowave – Maestro

MAESTRO-MD

Universal Premium High-End System dual-modality combining ultrasound and optoacoustics

Tomowave's Maestro-MD is an advanced medical imaging system that combines optical and acoustic technologies to provide high-resolution, real-time visualization of tissue structure and function. Designed for clinical and research applications, it enables early detection and monitoring of various diseases with unmatched precision and depth.

Precision Imaging

Revolutionizing Healthcare

TomoWave develops proprietary optoacoustic tomography and laser ultrasound systems for combined functional/molecular and anatomical imaging with applications in detection of cancer and image-guided interventions

LOIS-3D
Maestro
Symphony

MAESTRO-MD

Universal Premium High-End Dual Modality of Ultrasound combined and coregistered with optoacoustics

Clinical Applications

  1. Screening diagnostics of early-stage diseases:                                           a. vasculature and microvasculature in the liver and kidneys
     b. various heart conditions
     c. diabetic damage of microvasculature
  2. Differentiation of peripheral arteries, veins, and nerves
  3. Measurements of blood oxygenation in the vasculature, and microvasculature:      
      a. Monitoring placenta during pregnancy                                                    b. Oxygenation of the brain and other various organs                              c. Cancer diagnostics based on the density of angiogenesis                
          microvasculature and hypoxia of tumors (breast, etc)                             
  4. Detection and diagnostics of various cancers, lymph nodes
  5. Image-guided surgery: cancer, spine, vasculature, cosmetic
  6. Monitoring 3D temperature in the course of minimally invasive thermal therapy of cancer

MAESTRO-HR

Universal Premium Imaging System for vasculature, microvasculature, and measurement of SO2

  1. Spatial resolution: from 0.3mm for deep tissue (up to 50 mm) imaging to 0.05mm for subsurface (up to 8 mm) imaging
  2. Temporal resolution from 20 fps (OAT) to 300 fps (plane wave USI)
  3. Contrast/Sensitivity to optical absorption: dma~0.03/cm.
  4. Spectral imaging from 660 nm to 2300 nm for detection of arteries, veins and nerves and molecular imaging of contrast agents.
  5. Monitoring temperature distribution with video rate and precision of better than 0.50C.
  6. High-end ultrasound functions of A,B,C,M modes, color and power Doppler, shear wave elastography, and dynamic microvasculature, plane wave cardiac imaging, vector blood flow imaging of ultrasound contrast agents.
  7. Functional imaging of [SO2] by optoacoustic tomography.

MicroVascular Diseases

Global Health Problems: 18 Million people die every year prematurelyfrom Vascular Diseases because safe, accurate and inexpensive methods of early detection are not currently available.

Shortcomings of MRI

  • Too expensive - impractical for screening
  • Limited to visualizing only major blood vessels not micro-vessels
  • Requires toxic contrast agent
  • No measure of blood oxygen saturation
  • Requires interpretation by trained doctor

TomoWave has developed breakthrough optoacoustic ultrasound solutions to address these critical unmet needs

  • Tomowave – Maestro
  • Tomowave – Maestro

    Brain Vasculature

  • Tomowave – Maestro

    Foot Vasculature

*Foot vasculature image is a courtesy of our partner Prof. Chulhong Kim, POSTECH and Opticho (S. Korea)

Maestro-HR Ultrasonic and Optoacoustic Probes

High Frequency Probes

MODEL TYPE FREQUENCY APPLICATIONS
TWHF-65
LINEAR
65-35 MHz
Embryos, microvasculature, rat skin, zebrafish, mouse and rat eye anatomy
TWHF-42
LINEAR
42-18 MHz
Mouse, rat cardiovascular abdomen, reproductive system, rabbit eyes
TWHF-22
LINEAR
22-14 MHz
Rat, Rabbit cardiovascular, abdominal

Deep Tissue Imaging Probes

MODEL TYPE FREQUENCY APPLICATIONS
TWDT-14-F
LINEAR
14-6 MHz
Rat, Rabbit cardiovascular, abdominal, mouse brain
TWDT-11-F
LINEAR
11-4 MHz
Large animal abdomen, rat and rabbit cardiovascular
TWDT-04-F
PHASED
4-0.1 MHz
Large animal cardiovascular, abdominal, large vasculature

MAESTRO-RD

Universal Premium High-End System combined optacoustic molecular and ultrasound anatomical imaging enabling preclinical research

Maestro-RD provides 256 physical channels and data receive modes, which can be expanded to 512 and 1024 channels.

Bandwidth: 0.15M-27MHz ultrawide frequency range. Software Beamformer supports multiple transmit and receive modes. Ultra-sensitive ultrasonic transducers. Probe combination covers the entire ultrawide range of system sensitivity, 1D and 2D arrays are supported.

Maestro covers all functions of high-end ultrasound, with variety of functional modules: B mode, M mode, C mode, color Doppler, power Doppler, contrast imaging. Plane wave cardiac imaging, vector blood flow imaging. Plane wave ultra-high frame rate blood flow and contrast agent imaging. Shear wave elastography mode.

Microbubble tracking in a rodent brain.

Kidney

 High- Resolution Kidney

 

Liver

High-Resolution Liver

 

Computer-Controlled
Probe Holder for Maestro

  1. Animal platform with physiological monitoring under adjustable platform temperature: Simultaneously controls EKG, body temperature, and respiratory rhythm of experimental animals in real time.

  2. 3D position adjustment,
    High-strength alloy frame,
    Platforms for mouse and rat

Frequently Asked
Questions

The MAESTRO-MD device by Tomowave represents a cutting-edge advancement in biomedical imaging, integrating multi-modal technology to provide comprehensive diagnostic insights. Designed for clinical and research applications, MAESTRO-MD combines optoacoustic (photoacoustic) and ultrasound imaging in a single, non-invasive system, enabling high-resolution visualization of tissue structure and function in real time.

What is the MAESTRO device, and what makes it unique?

MAESTRO is a multi-modal imaging system developed by Tomowave that combines optoacoustic (photoacoustic) and ultrasound imaging technologies. Its unique integration allows for simultaneous visualization of both anatomical structures and functional information—such as blood oxygenation and molecular content—in real time, providing a comprehensive view of biological tissues.

What are the main clinical or research applications of the MAESTRO device?

The MAESTRO system is designed for a wide range of applications, including cancer detection and monitoring, assessment of vascular health, imaging of inflammatory conditions, and evaluation of tissue response to therapies. Its non-invasive nature and functional imaging capabilities make it valuable for both clinical diagnostics and biomedical research.

How does MAESTRO improve diagnostic accuracy compared to traditional imaging methods?

By combining ultrasound with optoacoustic imaging, MAESTRO provides both structural and molecular-level information in a single scan. This dual-modality approach enables more accurate detection of abnormalities, earlier diagnosis, and better monitoring of treatment outcomes—surpassing the limitations of imaging systems that rely solely on anatomical data.

Is the MAESTRO device safe for patients and research subjects?

Yes, MAESTRO is designed with safety in mind. It uses safe levels of near-infrared laser light and non-ionizing ultrasound energy, making it non-invasive and free from the risks associated with ionizing radiation. This makes it suitable for repeated imaging sessions and long-term monitoring.

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Kim Tillinghast

CPFA™, Principal, Partner

Kim Tillinghast began her career in the banking industry in 1985. She graduated with a degree in Finance from West Texas State University in 1990 and has continued her education by earning her Series 24 General Securities Principal Exam and Certified Plan Fiduciary Advisor (CPFA™). Shortly thereafter she started her brokerage career at a traditional wirehouse in downtown Los Angeles, California in 1991. After relocating to Orange County, Kim became an independent financial advisor in May of 1993. She brings over 37 years in the banking and finance industry with experience ranging from designing, developing, employing and maintaining complex investment strategies, Pension Plans, Employee Stock Option Plans, Corporate Finance, Estate Planning and Transition. Outside of her career, she served as Co-Chair of the Dallas County Susan G. Komen Race for the Cure 2013 and 2014 and currently serves on the Board of the Tillinghast Society, Inc. With a deep love for animals, she continues to volunteer for multiple emergency animal response teams including Red Rover, HSUS, UAN, ASPCA and volunteers weekly at the Irving Animal Shelter. Kim also loves worldwide adventure travel and has many amazing experiences visiting almost half of the world’s countries and all seven continents, twice.

Karthik Muraliraj

CFP®, ChFC®, CLU®, RMA®, Partner

Karthik Muraliraj was raised in Fort Worth, Texas, and developed an interest in investing and economics at a young age. After graduating from the University of Texas at Austin with a Bachelor of Arts in Economics and a minor in Business, he started his career as a financial professional in 2008. Throughout his career, Karthik has continued to educate himself by gaining multiple designations. Since moving to Dallas, he has been an active member in the community—volunteering with organizations such as the network of Indian Professionals, Dallas Autumn Ball and Reading Partners. Karthik is an avid sports fan and enjoys supporting his alma mater as a proud member of the Texas Exes Dallas Chapter. In his free time, Karthik enjoys cooking, travel, fitness and spending time with this wife, son, dog, and cat.

Crystal Arredondo

MBA, CDFA®, CPFA™, Partner

Crystal Arredondo was born and raised in Germany. She moved to Texas following her parents’ decision to retire after serving an overseas career in the Armed Forces. Seeing firsthand the difficult transition to civilian life after retirement, Crystal obtained her MBA in Finance at the University of North Texas and began her career as a financial advisor. In 2009, she completed the Retirement Planning Specialist Program at the Wharton School of Business, University of Pennsylvania. In 2018, she earned her designation of Certified Divorce Financial Analyst® (CDFA®). In 2022, she earned the additional designation as a Certified Plan Fiduciary Advisor (CPFA™). As the daughter of an immigrant mother, she especially enjoys helping women and business owners make decisions that affect their financial independence. She served as the 2015-16 Chair for the National Association of Women Business Owners (NAWBO) and 2016-17 Chair for the NAWBO Institute of Entrepreneurial Development.

Philip Strunk

CFP®, CPA, Partner

Philip Strunk is a native of Houston, TX. Philip earned his Bachelor of Business Administration and Masters in Professional Accounting from the University of Texas at Austin’s McCombs School of Business. He earned his designation as Certified Public Accountant (CPA) in 2004 and CERTIFIED FINANCIAL PLANNER (TM) certification in 2010. Having started his career with Deloitte & Touche, LLP in 2005, Philip spent a year and a half in Deloitte’s Audit and Assurance Services group and provided a variety of financial services for a number of Fortune 500 companies. He decided in late 2006 that his talent and passion for investments were best suited for working with smaller groups and individuals. After obtaining the required securities registrations and insurance licenses, Philip became a financial advisor. The impact was plainly visible and more fulfilling. Philip serves as the Investment Director for MPACT.

John C. Farris

CAP®, CFS®, Partner

John C. Farris is a founding partner and has more than forty years in both public and private business serving in a variety of management and leadership capacities. John completed the Retirement Planning Specialist Program at the Wharton School of Business at the University of Pennsylvania earning the Retirement Planning Specialist designation. John and his family have a history of philanthropic giving through numerous non-profit organizations. John recently completed his designation as a Chartered Advisor in Philanthropy® (CAP®). He is also a member of The International Association of Advisors in Philanthropy. His primary goal is to help people give intelligently with love and thereby experience the true joy of helping others. John lives in Park Cities and has served on the Public Works Advisory Council, as finance director of the BSA West Park District, the BSA Troop 82 Executive Board, and as a BSA Assistant Scoutmaster for Troop 82, Dallas, Texas.